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Article

Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolome

12 Mar 2018

Abstract excerpt

Trypanosoma cruzi parasites are the causative agents of Chagas disease. These parasites infect cardiac and gastrointestinal tissues, leading to local inflammation and tissue damage. Digestive Chagas disease is associated with perturbations in food absorption, intestinal traffic and defecation. However, the impact of T. cruzi infection on the gut microbiota and metabolome have yet to be characterized. In this...

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PMID: 29529084
DOI: 10.1371/journal.pntd.0006344

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