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Identification of cellular inhibitors against Chikungunya virus replication by a cDNA expression cloning combined with MinION sequencing.

Biochemical and biophysical research communications - 1 Oct 2020

Sakaguchi Shoichi, Suzuki Youichi, Emi Akino, Wu Hong, Nakano Takashi

Abstract excerpt

cDNA expression cloning has been shown to be a powerful approach in the search for cellular factors that control virus replication. In this study, cDNA library screening using a pool of cDNA derived from interferon-treated human cells was combined with the MinION sequencer to identify cellular genes inhibiting Chikungunya virus (CHIKV) replication. Challenge infection of CHIKV to Vero cells transduced with the...

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PMID: 32762941
DOI: 10.1016/j.bbrc.2020.07.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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