Article
Neutralization Analysis of a Chicken Single-Chain Variable Fragment Derived from an Immune Antibody Library Against Infectious Bronchitis Virus.
Viral immunology - 1 Sept 2015
Lin Yuan, Li Benqiang, Ye Jiaxin, Wang Man, Wang Jianhua, Zhang Ying, Zhu Jianguo
Abstract excerpt
Avian infectious bronchitis virus (IBV), which is prevalent in many countries causing severe economic loss to the poultry industry, causes infectious bronchitis (IB) in birds. Recombinant single-chain variable fragments (scFvs) have been proven to effectively inhibit many viruses, both in vitro and in vivo, and they could be a potential diagnostic and therapeutic reagent to control IB. In this study, six anti-IBV...
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