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Article

Complement factors and alpha‐fetoprotein as biomarkers for noninvasive prenatal diagnosis of neural tube defects

5 Aug 2020

Abstract excerpt

Neural tube defects (NTDs) are serious congenital malformations. In this study, we aimed to identify more specific and sensitive maternal serum biomarkers for noninvasive NTD screenings. We collected serum from 37 pregnant women carrying fetuses with NTDs and 38 pregnant women carrying normal fetuses. Isobaric tags for relative and absolute quantitation were conducted for differential proteomic analysis, and an...

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Share to Fetal and Pediatric Neurological Disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32761624
DOI: 10.1111/nyas.14443

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