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Human coelomic fluid investigation: A MS-based analytical approach to prenatal screening

16 Jul 2018

Abstract excerpt

Coelomic fluid (CF) is the earliest dynamic and complex fluid of the gestational sac. CF contains maternal cells and proteins produced by embryonic cells, tissues and excretions. The biochemical composition of CF is modified throughout the first trimester of pregnancy and its protein profile reflects both physiological/pathological changes affecting the embryo and mother. Identification of variations in the...

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PMID: 30030477
DOI: 10.1038/s41598-018-29384-9

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