Article
The diagnostic accuracy of maternal serum alpha-fetoprotein variants (AFP-L2 and AFP-L3) in predicting fetal open neural tube defects and abdominal wall defects.
Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2020
Chen Yiming, Wang Xue, Lu Sha, Huang Jianxia, Zhang Lidan, Hu Wensheng
Abstract excerpt
INTRODUCTION: To evaluate a risk model of the maternal serum α-fetoprotein variants L2 and L3 (AFP-L2 and AFP-L3) for predicting fetal open neural tube defects (ONTD) and abdominal wall defects (AWD). METHODS: Subjects were divided into the ONTD group (21), the AWD group (16) and the control group (38). Comparative analysis was performed using a risk model, receiver operating characteristic (ROC) curves and area...
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