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Article

Inter-individual differences in immune profiles of outbred rats screened for an emotional reactivity phenotype.

Journal of neuroimmunology - 15 Oct 2020

Isgor Ceylan, Aydin Cigdem, Oztan Ozge, Libreros Stephania, Iragavarapu-Charyulu Vijaya

Abstract excerpt

Inter-individual differences in emotional reactivity predict susceptibility versus resilience to mood pathology. Using experimentally-naïve outbred rats that vary in locomotor reactivity to the mild stress of an inescapable novel environment [i.e., top and bottom 1/3rd of the population identified as high responders (HR) and low responders (LR) respectively], we determined baseline variations in immune functions....

Topics

Adaptive Immunity
Animals
Cells, Cultured
Exploratory Behavior
Female
Immunity, Innate
Individuality
Locomotion
Male
Mood Disorders
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Rats, Sprague-Dawley

Source

Identifiers

PMID: 32750564
DOI: 10.1016/j.jneuroim.2020.577349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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