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Article

Identification of New Potential LncRNA Biomarkers in Hirschsprung Disease.

International journal of molecular sciences - 2 Aug 2020

Torroglosa Ana, Villalba-Benito Leticia, Fernández Raquel María, Luzón-Toro Berta, Moya-Jiménez María José, Antiñolo Guillermo, Borrego Salud

Abstract excerpt

Hirschsprung disease (HSCR) is a neurocristopathy defined by intestinal aganglionosis due to alterations during the development of the Enteric Nervous System (ENS). A wide spectrum of molecules involved in different signaling pathways and mechanisms have been described in HSCR onset. Among them, epigenetic mechanisms are gaining increasing relevance. In an effort to better understand the epigenetic basis of HSCR,...

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Identifiers

PMID: 32748823
DOI: 10.3390/ijms21155534
PMCID: PMC7432910

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