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Article

ChIP-Seq-Based Approach in Mouse Enteric Precursor Cells Reveals New Potential Genes with a Role in Enteric Nervous System Development and Hirschsprung Disease.

International journal of molecular sciences - 28 Nov 2020

Villalba-Benito Leticia, Torroglosa Ana, Luzón-Toro Berta, Fernández Raquel María, Moya-Jiménez María José, Antiñolo Guillermo, Borrego Salud

Abstract excerpt

Hirschsprung disease (HSCR) is a neurocristopathy characterized by intestinal aganglionosis which is attributed to a failure in neural crest cell (NCC) development during the embryonic stage. The colonization of the intestine by NCCs is a process finely controlled by a wide and complex gene regulatory system. Several genes have been associated with HSCR, but many aspects still remain poorly understood. The...

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Identifiers

PMID: 33260622
DOI: 10.3390/ijms21239061
PMCID: PMC7730166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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