Article
Age-stratified clinical performance and survival of patients with IDH-wildtype glioblastoma homogeneously treated by radiotherapy with concomitant and maintenance temozolomide.
Journal of cancer research and clinical oncology - 1 Jan 2021
Berger Kerstin, Turowski Bernd, Felsberg Jörg, Malzkorn Bastian, Reifenberger Guido, Steiger Hans-Jakob, Budach Wilfried, Haussmann Jan, Knipps Johannes, Rapp Marion, Hänggi Daniel, Sabel Michael, Mijderwijk Hendrik-Jan, Kamp Marcel A
Abstract excerpt
OBJECTIVE: Isocitrate dehydrogenase (IDH)-wildtype glioblastomas are the most malignant glial tumours. Median survival is only 14-16 months after diagnosis, with patients aged ≥ 65 years reportedly showing worse outcome. This study aimed to further evaluate the prognostic role of age in a homogenously treated patient cohort. METHODS: The study includes 132 IDH-wildtype glioblastoma patients treated between 2013...
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