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Differential mutation spectrum and immune landscape in African Americans versus Whites: A possible determinant to health disparity in head and neck cancer.

Cancer letters - 1 Nov 2020

Chaudhary Sanjib, Dam Vi, Ganguly Koelina, Sharma Sunandini, Atri Pranita, Chirravuri-Venkata Ramakanth, Cox Jesse L, Sayed Zafar, Jones Dwight T, Ganti Apar K, Ghersi Dario, Macha Muzafar A, Batra Surinder K

Abstract excerpt

African Americans (AA) with Head and Neck Squamous Cell Carcinoma (HNSCC) have a worse disease prognosis than White patients despite adjusting for socio-economic factors, suggesting the potential biological contribution. Therefore, we investigated the genomic and immunological components that drive the differential tumor biology among race. We utilized the cancer genome atlas and cancer digital archive of HNSCC...

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Identifiers

PMID: 32738272
DOI: 10.1016/j.canlet.2020.07.029
PMCID: PMC8432304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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