Article
The effect of CYP3A4 genetic variants on the susceptibility to chronic obstructive pulmonary disease in the Hainan Han population.
Genomics - 1 Nov 2020
Shi Huifang, Xu Jianguang, Feng Qiong, Sun Juan, Yang Yixiu, Zhao Jie, Zhou Xiaoli, Niu Huan, He Ping, Liu Jianfang, Li Quanni, Ding Yipeng
Abstract excerpt
PURPOSE: Genetic polymorphisms act a crucial role in chronic obstructive pulmonary disease (COPD) progression. This study aimed to investigate the correlation between CYP3A4 variants and COPD risk. METHODS: We carried out a case-control study of 821 individuals (313 patients and 508 healthy subjects) to identify the correlation of CYP3A4 SNPs with COPD risk in the Hainan Han population. The association was...
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