Article
Targeted next-generation sequencing reveals molecular heterogeneity in non-chronic lymphocytic leukemia clonal B-cell lymphocytosis.
Hematological oncology - 1 Dec 2020
Defrancesco Irene, Zibellini Silvia, Boveri Emanuela, Frigeni Marco, Ferretti Virginia Valeria, Rizzo Ettore, Bonometti Arturo, Capuano Francesca, Candido Chiara, Rattotti Sara, Tenore Annamaria, Picone Cristina, Flospergher Elena, Zerbi Caterina, Bergamini Fabio, Fabbri Nicole, Cristinelli Caterina, Varettoni Marzia, Paulli Marco, Arcaini Luca
Abstract excerpt
Non-chronic lymphocytic leukemia (non-CLL) clonal B-cell lymphocytosis (CBL) encompasses a heterogeneous group of hematologic disorders that are still poorly understood. To shed light on their biological aspects, we retrospectively analyzed a highly selected series of 28 patients, who had a clonal B-cell population in the peripheral blood and in the bone marrow, without evidence of lymphoma. Extended targeted...
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