Article
A mutation in monoamine oxidase (MAO) affects the evolution of stress behavior in the blind cavefish Astyanax mexicanus.
The Journal of experimental biology - 28 Sept 2020
Pierre Constance, Pradère Naomie, Froc Cynthia, Ornelas-García Patricia, Callebert Jacques, Rétaux Sylvie
Abstract excerpt
The neurotransmitter serotonin controls a variety of physiological and behavioral processes. In humans, mutations affecting monoamine oxidase (MAO), the serotonin-degrading enzyme, are highly deleterious. Yet, blind cavefish of the species Astyanax mexicanus carry a partial loss-of-function mutation in MAO (P106L) and thrive in their subterranean environment. Here, we established four fish lines, corresponding to...
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