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Article

Tumor progression locus 2 (TPL2) in tumor-promoting Inflammation, Tumorigenesis and Tumor Immunity.

Theranostics - 1 Jan 2020

Njunge Lucy Wanjiru, Estania Andreanne Poppy, Guo Yao, Liu Wanqian, Yang Li

Abstract excerpt

Over the years, tumor progression locus 2 (TPL2) has been identified as an essential modulator of immune responses that conveys inflammatory signals to downstream effectors, subsequently modulating the generation and function of inflammatory cells. TPL2 is also differentially expressed and activated in several cancers, where it is associated with increased inflammation, malignant transformation, angiogenesis,...

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Identifiers

PMID: 32724474
DOI: 10.7150/thno.45848
PMCID: PMC7381748

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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