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Article

The role of TPH2 variant rs4570625 in shaping infant attention to social signals.

Infant behavior & development - 1 Aug 2020

Kataja Eeva-Leena, Leppänen Jukka M, Kantojärvi Katri, Pelto Juho, Häikiö Tuomo, Korja Riikka, Nolvi Saara, Karlsson Hasse, Paunio Tiina, Karlsson Linnea

Abstract excerpt

TPH2, the rate-limiting enzyme in the synthesis of serotonin, has been connected to several psychiatric outcomes. Its allelic variant, rs4570625, has been found to relate to individual differences in cognitive and emotion regulation during infancy with T-carriers of rs4570625 showing a relatively heightened attention bias for fearful faces. A significant gene-environment interaction was also reported with the...

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PMID: 32711172
DOI: 10.1016/j.infbeh.2020.101471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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