Article
Extra-gastrointestinal stromal tumor arising in the lesser omentum with a platelet-derived growth factor receptor alpha (PDGFRA) mutation: a case report and literature review.
World journal of surgical oncology - 23 Jul 2020
Kanamori Kohei, Yamagata Yukinori, Honma Yoshitaka, Date Keiichi, Wada Takeyuki, Hayashi Tsutomu, Otsuki Sho, Sekine Shigeki, Yoshikawa Takaki, Katai Hitoshi, Nishida Toshiro
Abstract excerpt
BACKGROUND: Gastrointestinal stromal tumors (GIST) arising from sites other than the gastrointestinal (GI) tract, termed extra-gastrointestinal stromal tumors (EGIST), are rare. Among EGIST, those with platelet-derived growth factor receptor alpha (PDGFRA) mutations are even rarer, with only a few cases reported. About 80% of GIST has KIT mutations, and 10% of GIST have PDGFRA mutations, which commonly affect the...
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