Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of histone H3 trimethylation on lysine 27 and nuclear expression of transducin-like enhancer 1 in primary intracranial sarcoma, DICER1-mutant.

Histopathology - 1 Jan 2021

Alexandrescu Sanda, Meredith David M, Lidov Hart G, Alaggio Rita, Novello Mariangela, Ligon Keith L, Vargas Sara O

Abstract excerpt

AIMS: Primary intracranial sarcoma, DICER1-mutant is a recently described central nervous system tumour with specific genomic and DNA-methylation profiles. Although some of its histological features (focal spindle-cell morphology, intracytoplasmic eosinophilic granules, and focal heterologous differentiation) are common across most reported cases, the presence of significant histological variability and the lack...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to DEAD-box RNA Helicases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histones

Share to Lysine

Share to Methylation

Share to Ribonuclease III

Share to Sarcoma

Share to Transducin

Source

Identifiers

PMID: 32692439
DOI: 10.1111/his.14217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of histone H3 trimethylation on lysine 27 and nuclear expression of transducin-like enhancer 1 in primary intracranial sarcoma, DICER1-mutant.PMID 32692439Read ↗

DICER1-associated central nervous system sarcoma in children: comprehensive clinicopathologic and genetic analysis of a newly described rare tumor.Semantic proximity Read ↗

A Rare Adult Primary Intracranial Sarcoma, DICER1-Mutant Identified by Epigenomic Profiling: A Case ReportSemantic proximity Read ↗

All pineal tumors expressing germ cell tumor markers are not necessarily germ cell tumors: histopathological and molecular study of a midline primary intracranial sarcoma DICER1-mutant.Semantic proximity Read ↗

DICER1-Associated Central Nervous System Sarcoma with Neural Lineage Differentiation: A Case ReportSemantic proximity Read ↗

[Primary intracranial DICER1-mutant sarcoma: a clinicopathological analysis of seven cases].Semantic proximity Read ↗

DICER1-associated central nervous system sarcoma with neural lineage differentiation: a case report.Semantic proximity Read ↗

Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.Semantic proximity Read ↗

Rare child primary intracranial sarcoma associated with DICER1 mutation: a case report and review of the literature.Semantic proximity Read ↗

DICER1 mutations in primary central nervous system tumors: new insights into histologies, mutations, and prognosis.Semantic proximity Read ↗

From Malignant Thyroid Teratoma to Thyroblastoma: Evolution of a Newly-recognized DICER1 -associated Malignancy.Semantic proximity Read ↗

Genomic characterization of DICER1-associated neoplasms uncovers molecular classes.Semantic proximity Read ↗

Primary central nervous system sarcoma with DICER1 mutation-treatment results of a novel molecular entity in pediatric Peruvian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.