Primary central nervous system sarcoma with DICER1 mutation-treatment results of a novel molecular entity in pediatric Peruvian patients.

doi:10.1002/cncr.33977

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Article

Primary central nervous system sarcoma with DICER1 mutation-treatment results of a novel molecular entity in pediatric Peruvian patients.

Cancer - 15 Feb 2022

Diaz Coronado Rosdali Y, Mynarek Martin, Koelsche Christian, Mora Alferez Pamela, Casavilca Zambrano Sandro, Wachtel Aptowitzer Antonio, Sahm Felix, von Deimling Andreas, Schüller Ulrich, Spohn Michael, Sturm Dominik, Pfister Stefan M, Morales La Madrid Andres, Sernaque Quintana Raymundo, Sarria Bardales Gustavo, Negreiros Chinchihuara Tatiana, Ojeda Medina Luis, Garcia-Corrochano Medina Pamela, Campos Sanchez Danny A, Ponce Farfan Jimena, Rutkowski Stefan, Garcia Leon Juan L

Abstract excerpt

BACKGROUND: A high frequency of primary central nervous system (CNS) sarcomas was observed in Peru. This article describes the clinical characteristics, biological characteristics, and outcome of 70 pediatric patients. METHODS: Data from 70 pediatric patients with primary CNS sarcomas diagnosed between January 2005 and June 2018 were analyzed. DNA methylation profiling from 28 tumors and gene panel sequencing...

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PMID: 34674226
DOI: 10.1002/cncr.33977

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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