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Identification of Potential Antiviral Lead Inhibitors Against Sars-Cov-2 Main Protease: Structure-Guided Virtual Screening, Docking, Adme, and Md Simulation Based Approach

2023-05-25

Abstract excerpt

The novel coronavirus disease (COVID-19) is caused by a new strain of the virus SARS-CoV-2 in December 2019 that affected millions of people worldwide and led to severe health concerns and economic burden. The key factors such as vaccine resistance, inefficacy, and continuous gene mutations drove us to identify novel drug candidates. The main protease enzyme (Mpro) of SARS-CoV-2 was identified as a drug target sin...

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Literature Corpus work: cf8805ea-1688-54c2-b8ab-423009d2e500
DOI: 10.2139/ssrn.4457340

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