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Article

Establishment and characterization of Neu1-knockout zebrafish and its abnormal clinical phenotypes.

The Biochemical journal - 14 Aug 2020

Okada Keiji, Takase Ryo, Hamaoka Yurie, Honda Akinobu, Ikeda Asami, Hokazono Yoichiro, Maeda Yutaro, Hayasaka Oki, Kotani Tomonari, Komatsu Masaharu, Shiozaki Kazuhiro

Abstract excerpt

Mammalian sialidase Neu1 is involved in various physiological functions, including cell adhesion, differentiation, cancer metastasis, and diabetes through lysosomal catabolism and desialylation of glycoproteins at the plasma membrane. Various animal models have been established to further explore the functions of vertebrate Neu1. The present study focused on zebrafish (Danio rerio) belonging to Cypriniformes as...

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PMID: 32686823
DOI: 10.1042/BCJ20200348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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