Article
A Dinucleotide Deletion in the CD24 Gene Is a Potential Risk Factor for Colorectal Cancer.
The American surgeon - 1 May 2020
Segev Lior, Naboishchikov Ilana, Kazanov Diana, Bernstein Ezra, Shaked Meital, Arber Nadir, Shapira Shiran
Abstract excerpt
BACKGROUND: CD24 is a sialoglycoprotein anchored to the cell surface via glycosylphosphatidylinositol and is involved in intracellular signaling processes. It plays an important role in the early stages of the multistep process of colorectal carcinogenesis. Several single nucleotide polymorphisms in the CD24 gene are reported to exert a diverse effect on cancer risk. We aimed to elucidate whether CD24 TG/del...
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