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Article

Avasimibe inhibits the proliferation, migration and invasion of glioma cells by suppressing linc00339

16 Jul 2020

Abstract excerpt

Glioma is one of the most destructive human tumours. Although standard treatment has improved the prognosis for glioma patients, the survival of glioma patients is still unsatisfactory. Avasimibe, an effective inhibitor of cholesterol acyltransferase 1 (ACAT1), has shown anti-tumour efficacy in many kinds of tumours. However, its role and related mechanism in glioma has not been fully elucidated. In the present...

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PMID: 32682982
DOI: 10.1016/j.biopha.2020.110508

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