Article
Coronary artery disease and the risk-associated LPA variants, rs3798220 and rs10455872, in patients with suspected familial hypercholesterolaemia.
Clinica chimica acta; international journal of clinical chemistry - 1 Nov 2020
Page Michael M, Ellis Katrina L, Pang Jing, Chan Dick C, Hooper Amanda J, Bell Damon A, Burnett John R, Watts Gerald F
Abstract excerpt
BACKGROUND: The rs3798220 and rs10455872 single nucleotide polymorphisms (SNPs) in LPA are associated with increased plasma concentrations of lipoprotein(a) [Lp(a)] and coronary artery disease (CAD). METHODS: We investigated the association between rs3798220 and rs10455872 and prevalent CAD in 763 patients with suspected familial hypercholesterolaemia (FH). The rs3798220 and SNPs in LPA were detected...
