Article
Adjuvant Hepatic Artery Infusion Chemotherapy is Associated With Improved Survival Regardless of KRAS Mutation Status in Patients With Resected Colorectal Liver Metastases: A Retrospective Analysis of 674 Patients.
Annals of surgery - 1 Aug 2020
Gholami Sepideh, Kemeny Nancy E, Boucher Taryn M, Gönen Mithat, Cercek Andrea, Kingham T Peter, Balachandran Vinod, Allen Peter, DeMatteo Ronald, Drebin Jeffrey, Jarnagin William, D'Angelica Michael
Abstract excerpt
OBJECTIVE: To investigate the impact of adjuvant hepatic artery infusion (HAI) in relation to KRAS mutational status in patients with resected colorectal cancer liver metastases (CRLM). BACKGROUND: Patients with KRAS-mutated CRLM have worse outcomes after resection. Adjuvant HAI chemotherapy improves overall survival after liver resection. METHODS: Patients with resected CRLM treated at MSKCC with and without...
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