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Article

Neutrophil Extracellular Trap Degradation by Differently Polarized Macrophage Subsets.

Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2020

Haider Patrick, Kral-Pointner Julia B, Mayer Julia, Richter Manuela, Kaun Christoph, Brostjan Christine, Eilenberg Wolf, Fischer Michael B, Speidl Walter S, Hengstenberg Christian, Huber Kurt, Wojta Johann, Hohensinner Philipp

Abstract excerpt

OBJECTIVE: Macrophages are immune cells, capable to remodel the extracellular matrix, which can harbor extracellular DNA incorporated into neutrophil extracellular traps (NETs). To study the breakdown of NETs we studied the capability of macrophage subsets to degrade these structures in vitro and in vivo in a murine thrombosis model. Furthermore, we analyzed human abdominal aortic aneurysm samples in support of...

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Identifiers

PMID: 32673525
DOI: 10.1161/ATVBAHA.120.314883
PMCID: PMC7447175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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