Article
miR-215 Inhibits Colorectal Cancer Cell Migration and Invasion via Targeting Stearoyl-CoA Desaturase.
Computational and mathematical methods in medicine - 1 Jan 2020
Xu Xinhua, Ding Yan, Yao Jun, Wei Zhiping, Jin Haipeng, Chen Chen, Feng Jun, Ying Rongbiao
Abstract excerpt
BACKGROUND: This study was aimed at exploring the effects of miR-215 and its target gene stearoyl-CoA desaturase (SCD) on colorectal cancer (CRC) cell migration and invasion. METHODS: Here, we analyzed the relationship between miR-215 and SCD, as well as the regulation of miR-215 on CRC cells. We constructed wild-type and mutant plasmids of SCD to identify whether SCD was a target gene of miR-215 by using a...
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