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Article

Integrated lipidomics and transcriptomic analysis of peripheral blood reveals significantly enriched pathways in type 2 diabetes mellitus.

BMC medical genomics - 1 Jan 2013

Zhao Chen, Mao Jinghe, Ai Junmei, Shenwu Ming, Shi Tieliu, Zhang Daqing, Wang Xiaonan, Wang Yunliang, Deng Youping

Abstract excerpt

BACKGROUND: Insulin resistance is a key element in the pathogenesis of type 2 diabetes mellitus. Plasma free fatty acids were assumed to mediate the insulin resistance, while the relationship between lipid and glucose disposal remains to be demonstrated across liver, skeletal muscle and blood. METHODS: We profiled both lipidomics and gene expression of 144 total peripheral blood samples, 84 from patients with T2D...

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Identifiers

PMID: 23369247
DOI: 10.1186/1755-8794-6-S1-S12
PMCID: PMC3552685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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