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Article

Genetic polymorphisms in serine protease inhibitor Kazal-type 5 and risk of atopic dermatitis: A meta-analysis.

Medicine - 10 Jul 2020

Li Yunling, Li Yin, Li Wei, Guo Xiaoxuan, Zhou Sha, Zheng Huiwen

Abstract excerpt

BACKGROUND: This study aimed to investigate the role of serine protease inhibitor Kazal-type 5 (SPINK5) polymorphisms (Asn368Ser, Asp386Asn and Glu420Lys) and the risk of atopic dermatitis (AD). METHODS: Studies associated with SPINK5 mutations and AD risk were searched from three databases, including PubMed, Embase, and Cochrane library, with a retrieval deadline of April 22, 2019. An odds ratio (OR) with a 95%...

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Identifiers

PMID: 32664181
DOI: 10.1097/MD.0000000000021256
PMCID: PMC7360313

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