Article
Near Real-Time Identification of Recent Human Immunodeficiency Virus Transmissions, Transmitted Drug Resistance Mutations, and Transmission Networks by Multiplexed Primer ID-Next-Generation Sequencing in North Carolina.
The Journal of infectious diseases - 3 Mar 2021
Zhou Shuntai, Sizemore Sabrina, Moeser Matt, Zimmerman Scott, Samoff Erika, Mobley Victoria, Frost Simon, Cressman Andy, Clark Michael, Skelly Tara, Kelkar Hemant, Veluvolu Umadevi, Jones Corbin, Eron Joseph, Cohen Myron, Nelson Julie A E, Swanstrom Ronald, Dennis Ann M
Abstract excerpt
BACKGROUND: The identification of recent human immunodeficiency virus (HIV) 1 infections among people with new HIV diagnoses is important to both tailoring and assessing the impact of HIV-1 prevention strategies. METHODS: We developed a multiplexed Primer ID-next-generation sequencing approach to identify recent infections by measuring the intrahost viral diversity over multiple regions of the HIV-1 genome, in...
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