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Article

Molecular and functional characterization of urine-derived podocytes from patients with Alport syndrome.

The Journal of pathology - 1 Sept 2020

Iampietro Corinne, Bellucci Linda, Arcolino Fanny O, Arigoni Maddalena, Alessandri Luca, Gomez Yonathan, Papadimitriou Elli, Calogero Raffaele A, Cocchi Enrico, Van Den Heuvel Lambertus, Levtchenko Elena, Bussolati Benedetta

Abstract excerpt

Alport syndrome (AS) is a genetic disorder involving mutations in the genes encoding collagen IV α3, α4 or α5 chains, resulting in the impairment of glomerular basement membrane. Podocytes are responsible for production and correct assembly of collagen IV isoforms; however, data on the phenotypic characteristics of human AS podocytes and their functional alterations are currently limited. The evident loss of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 32652570
DOI: 10.1002/path.5496
PMCID: PMC7589231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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