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Combining host-derived biomarkers with patient characteristics improves signature performance in predicting tuberculosis treatment outcomes

9 Jul 2020

Abstract excerpt

Tuberculosis (TB) is a global health concern. Treatment is prolonged, and patients on anti-TB therapy (ATT) often experience treatment failure for various reasons. There is an urgent need to identify signatures for early detection of failure and initiation of a treatment switch.We investigated how gene biomarkers and/or basic patient characteristics could be used to define signatures for treatment outcomes in...

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PMID: 32647325
DOI: 10.1038/s42003-020-1087-x

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