Article
Replication of a Dog-Origin H6N1 Influenza Virus in Cell Culture and Mice.
Viruses - 30 Jun 2020
Tsai Shou-Kuan, Shih Cheng-Hsin, Chang Hui-Wen, Teng Kuang-Huan, Hsu Wei-En, Lin Han-Jia, Lin Han-You, Huang Ching-Huei, Chen Hui-Wen, Wang Lih-Chiann
Abstract excerpt
The world's first natural avian-origin H6N1 influenza A virus infection case in dogs was confirmed in Taiwan in 2014. The H6N1 virus in chickens has been endemic in Taiwan since 1972. Whether the dog H6N1 virus has interspecies transmission potential is the key issue we aim to understand. Following one virus passage in embryonated eggs and two further passages in MDCK cells, we obtained two virus derivatives,...
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