Article
SLC2A3 rs12842 polymorphism and risk for Alzheimer's disease.
Neurological research - 1 Oct 2020
Arseniou Stylianos, Siokas Vasileios, Aloizou Athina-Maria, Stamati Polyxeni, Mentis Alexios-Fotios A, Tsouris Zisis, Dastamani Metaxia, Peristeri Eleni, Valotassiou Varvara, Bogdanos Dimitrios P, Hadjigeorgiou Georgios M, Dardiotis Efthimios
Abstract excerpt
BACKGROUND: Many studies support the hypothesis that brain glucose dysregulation contributes to neurodegeneration and disease progression. The SLC2A3 gene encodes the Neuronal Glucose Transporter 3 (GLUT3), a critical molecule for glucose transport into the neuron. The GLUT3 rs12842 polymorphism has been associated with an increased risk for attention-deficit/hyperactivity disorder (ADHD). Epidemiological and...
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