Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mood-Stabilizing Antiepileptic Treatment Response in Bipolar Disorder: A Genome-Wide Association Study.

Clinical pharmacology and therapeutics - 1 Dec 2020

Ho Ada Man-Choi, Coombes Brandon J, Nguyen Thanh Thanh L, Liu Duan, McElroy Susan L, Singh Balwinder, Nassan Malik, Colby Colin L, Larrabee Beth R, Weinshilboum Richard M, Frye Mark A, Biernacka Joanna M

Abstract excerpt

Several antiepileptic drugs (AEDs) have US Food and Drug Administration (FDA) approval for use as mood stabilizers in bipolar disorder (BD), but not all BD patients respond to these AED mood stabilizers (AED-MSs). To identify genetic polymorphisms that contribute to the variability in AED-MS response, we performed a discovery genome-wide association study (GWAS) of 199 BD patients from the Mayo Clinic Bipolar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Affect
Share to Anticonvulsants

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antimanic Agents

Share to Lamotrigine

Share to Multidrug Resistance-Associated Proteins

Share to Pharmacogenomic Variants

Share to Thrombospondins

Share to Valproic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 32627186
DOI: 10.1002/cpt.1982
PMCID: PMC7669647

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mood-Stabilizing Antiepileptic Treatment Response in Bipolar Disorder: A Genome-Wide Association Study.PMID 32627186Read ↗

Genetics and Antiepileptic Mood Stabilizer Treatment Response in Bipolar Disorder: What do we Know?Semantic proximity Read ↗

Pharmacogenomics of antiepileptic drug mood stabilizer treatment response in bipolar disorder: A MoStGen Consortium study.Semantic proximity Read ↗

Antipsychotic Use in Bipolar Disorder: Clinical and Genomic Correlates– A Mayo Clinic Bipolar Disorder Biobank StudySemantic proximity Read ↗

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.Semantic proximity Read ↗

Pharmacogenomics of Bipolar DisorderSemantic proximity Read ↗

Can the response to mood stabilizers be predicted in bipolar disorder?Semantic proximity Read ↗

Pharmacogenetic Predictors of Cannabidiol Response and Tolerability in Treatment-Resistant Epilepsy.Semantic proximity Read ↗

New "drugs and targets" in the GWAS era of bipolar disorder.Semantic proximity Read ↗

A translational multimodal machine-learning prototype predicting valproate response in epilepsy treatmentSemantic proximity Read ↗

Genetics of psychotropic medication induced side effects in two independent samples of bipolar patients.Semantic proximity Read ↗

Recent Trends on the Role of Epigenomics, Metabolomics and Noncoding RNAs in Rationalizing Mood Stabilizing TreatmentSemantic proximity Read ↗

Genome-wide association studies of placebo and duloxetine response in major depressive disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.