Article
Can the response to mood stabilizers be predicted in bipolar disorder?
Frontiers in bioscience (Elite edition) - 1 Jan 2014
Geoffroy Pierre Alexis, Bellivier Frank, Leboyer Marion, Etain Bruno
Abstract excerpt
Bipolar disorder (BD) is a severe chronic multifactorial disease that requires maintenance therapy with mood stabilizers (MS). Even with medications, the rate of response among patients with BD is low and the risk of relapse is high. Therefore, in this context of the urgent need for reliable and reproducible predictors of individual responses to MS, pharmacogenetics research is expected to provide helpful...
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