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Article

A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells.

Stem cell reports - 14 Jul 2020

Kaserman Joseph E, Hurley Killian, Dodge Mark, Villacorta-Martin Carlos, Vedaie Marall, Jean Jyh-Chang, Liberti Derek C, James Marianne F, Higgins Michelle I, Lee Nora J, Washko George R, San Jose Estepar Raul, Teckman Jeffrey, Kotton Darrell N, Wilson Andrew A

Abstract excerpt

Individuals with the genetic disorder alpha-1 antitrypsin deficiency (AATD) are at risk of developing lung and liver disease. Patient induced pluripotent stem cells (iPSCs) have been found to model features of AATD pathogenesis but only a handful of AATD patient iPSC lines have been published. To capture the significant phenotypic diversity of the patient population, we describe here the establishment and...

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Identifiers

PMID: 32619491
DOI: 10.1016/j.stemcr.2020.06.006
PMCID: PMC7363960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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