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Article

ACTL6A suppresses p21Cip1 expression to enhance the epidermal squamous cell carcinoma phenotype.

Oncogene - 1 Sept 2020

Shrestha Suruchi, Adhikary Gautam, Xu Wen, Kandasamy Sivaveera, Eckert Richard L

Abstract excerpt

Epidermal squamous cell carcinoma (SCC) is a common and highly invasive form of cancer. SCC arises due to ultraviolet light exposure and is associated with increased expression of pro-cancer genes and reduced expression of cancer suppressors. Actin-Like Protein 6A (ACTL6A, BAF53a) is an important protein subunit of the SWI/SNF epigenetic chromatin regulatory complex. ACTL6A is elevated in cancer cells and has...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32616890
DOI: 10.1038/s41388-020-1371-8
PMCID: PMC7483332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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