Article
Promising application of monoclonal antibody against chikungunya virus E1-antigen across genotypes in immunochromatographic rapid diagnostic tests.
Virology journal - 2 Jul 2020
Suzuki Keita, Huits Ralph, Phadungsombat Juthamas, Tuekprakhon Aekkachai, Nakayama Emi E, van den Berg Riemsdijk, Barbé Barbara, Cnops Lieselotte, Rahim Rummana, Hasan Abu, Iwamoto Hisahiko, Leaungwutiwong Pornsawan, van Esbroeck Marjan, Rahman Mizanur, Shioda Tatsuo
Abstract excerpt
BACKGROUND: Three different genotypes of chikungunya virus (CHIKV) have been classified: East/Central/South African (ECSA), West African (WA), and Asian. Previously, a rapid immunochromatographic (IC) test detecting CHIKV E1-antigen showed high sensitivity for certain ECSA-genotype viruses, but this test showed poor performance against the Asian-genotype virus that is spreading in the American continents. We...
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