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Article

Developing a sensitive HBV genotyping assay for HBV DNA suppressed patients using both DNA and RNA sequencing.

Journal of medical virology - 1 Dec 2020

Liu Yang, May Lindsey, Liu Xinan, Martin Ross, Svarovskaia Evguenia, Gaggar Anuj, Mo Hongmei, Feierbach Becket

Abstract excerpt

Hepatitis B virus (HBV) genotypes impact treatment outcomes and disease progression. The current genotyping methods have limitations in patients with low HBV viral load. In this study, a more sensitive assay has been developed for determining the HBV genotype in HBV DNA suppressed patients. Fifty-five serum samples from 55 chronic hepatitis B patients (HBeAg-, n = 20; HBeAg+, n = 35) across genotypes A to H with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32609910
DOI: 10.1002/jmv.26249

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