Article
MutantHuntWGS: A Pipeline for Identifying Saccharomyces cerevisiae Mutations.
G3 (Bethesda, Md.) - 2 Sept 2020
Ellison Mitchell A, Walker Jennifer L, Ropp Patrick J, Durrant Jacob D, Arndt Karen M
Abstract excerpt
MutantHuntWGS is a user-friendly pipeline for analyzing Saccharomyces cerevisiae whole-genome sequencing data. It uses available open-source programs to: (1) perform sequence alignments for paired and single-end reads, (2) call variants, and (3) predict variant effect and severity. MutantHuntWGS outputs a shortlist of variants while also enabling access to all intermediate files. To demonstrate its utility, we...
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