Article
Power of a genome scan to detect and locate quantitative trait loci in cattle using dense single nucleotide polymorphisms.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie - 1 Apr 2010
MacLeod I M, Hayes B J, Savin K W, Chamberlain A J, McPartlan H C, Goddard M E
Abstract excerpt
There is increasing use of dense single nucleotide polymorphisms (SNPs) for whole-genome association studies (WGAS) in livestock to map and identify quantitative trait loci (QTL). These studies rely on linkage disequilibrium (LD) to detect an association between SNP genotypes and phenotypes. The power and precision of these WGAS are unknown, and will depend on the extent of LD in the experimental population. One...
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