Article
[Epidemiology and diagnosis of mutations in the ALK gene in patients with non-small cell lung cancer in the Moscow region].
Arkhiv patologii - 1 Jan 2020
Byakhova M M, Zavalishina L E, AndreevA Yu Yu, Tyulyandin S A, Tsimafeyeu I V, Imyanitov E N, Savelov N A, Demidova I A, Kekeyeva T V, Mueva N M, Frank G A
Abstract excerpt
AIM OF STUDY: To determine a diagnostic algorithm for detecting translocation of the ALK gene and its frequency in the Moscow region. MATERIALS AND METHODS: During the priod between 2014 and 2018 (inclusive), 488 patients without activating mutations in the EGFR gene in the Moscow region were tested. To detect translocation of the ALK gene, fluorescence in situ hybridization (FISH) methods, an immunohistochemical...
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