Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Live births in women with recurrent hydatidiform mole and two NLRP7 mutations.

Reproductive biomedicine online - 1 Jul 2015

Akoury Elie, Gupta Neerja, Bagga Rashmi, Brown Stephen, Déry Christine, Kabra Madhulika, Srinivasan Radhika, Slim Rima

Abstract excerpt

Hydatidiform mole (HM) is an aberrant human pregnancy with abnormal embryonic development and excessive proliferation of the trophoblast. Recessive mutations in NLRP7 are responsible for recurrent HM (RHM). Women with recessive NLRP7 mutations fail to have normal pregnancies from spontaneous conceptions with the exception of three out of 131 reported patients. Because there is no treatment for RHM and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Fertilization in Vitro

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydatidiform Mole

Share to Infertility, Female

Share to Live Birth

Share to Mutation, Missense

Share to Pregnancy

Share to Pregnancy Outcome

Source

Identifiers

PMID: 25982095
DOI: 10.1016/j.rbmo.2015.03.011

Genes

NLRP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Live births in women with recurrent hydatidiform mole and two NLRP7 mutations.PMID 25982095Read ↗

Recurrent hydatidiform mole: detection of two novel mutations in the NLRP7 gene in two Egyptian families.Semantic proximity Read ↗

Pregnancy after oocyte donation in a patient with NLRP7 gene mutations and recurrent molar hydatidiform pregnancies.Semantic proximity Read ↗

The genetics of recurrent hydatidiform moles in China: correlations between NLRP7 mutations, molar genotypes and reproductive outcomes.Semantic proximity Read ↗

Maternal NLRP7 and C6orf221 variants are not a common risk factor for androgenetic moles, triploidy and recurrent miscarriage.Semantic proximity Read ↗

The p.L750V mutation in the NLRP7 gene is frequent in Mexican patients with recurrent molar pregnancies and is not associated with recurrent pregnancy loss.Semantic proximity Read ↗

NLRP7 in the spectrum of reproductive wastage: rare non-synonymous variants confer genetic susceptibility to recurrent reproductive wastage.Semantic proximity Read ↗

Recurrent pregnancy loss in a woman with NLRP7 mutation: not all molar pregnancies can be easily classified as either "partial" or "complete" hydatidiform moles.Semantic proximity Read ↗

A Novel Mutation in NLRP7 Related to Recurrent Hydatidiform Mole and Reproductive Failure.Semantic proximity Read ↗

Novel NLRP7 mutations in familial recurrent hydatidiform mole: are NLRP7 mutations a risk for recurrent reproductive wastage?Semantic proximity Read ↗

Biallelic NLRP7 variants in patients with recurrent hydatidiform mole: A review and expert consensus.Semantic proximity Read ↗

The genetics of hydatidiform moles: new lights on an ancient disease.Semantic proximity Read ↗

Women heterozygous for NALP7/NLRP7 mutations are at risk for reproductive wastage: report of two novel mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.