Article
Recurrent complete hydatidiform mole: where we are, is there a safe gestational horizon? Opinion and mini-review.
Journal of assisted reproduction and genetics - 1 Jun 2018
Kalogiannidis Ioannis, Kalinderi Kallirhoe, Kalinderis Michail, Miliaras Dimosthenis, Tarlatzis Basil, Athanasiadis Apostolos
Abstract excerpt
Benign hydatidiform mole, complete or partial, is the most common type of gestational trophoblastic disease (GTD) characterised by excessive trophoblastic proliferation and abnormal embryonic development. Although most complete hydatidiform moles (CHMs) are diploid androgenetic, a few cases of CHMs are biparental, characterised by recurrence and familial clustering. In these rare cases, mutations in NLRP7 or...
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