Article
CYP2D6 does not impact on breast cancer-free survival in Southeast Mexican patients under tamoxifen treatment.
Personalized medicine - 1 Jul 2020
Jorge-Aarón Rangel-Méndez, Rodrigo Rubi-Castellanos, de Jesús Ascencio-Montiel Iván, Esther Moo-Puc Rosa
Abstract excerpt
Aim: We conducted a retrospective analysis in 71 Mexican Mestizo patients to evaluate the breast cancer-free survival (BCFS) among the inferred genetic phenotypes (GP) of CYP2D6. Patients & methods:CYP2D6 was genotyped through Taqman-probe analysis; GP were inferred according to international guidelines. The BCFS was estimated through Kaplan-Meier method and analyzed with a log-rank test; hazard ratios were...
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