Article
CYP2D6 polymorphisms influence tamoxifen treatment outcomes in breast cancer patients: a meta-analysis.
Cancer chemotherapy and pharmacology - 1 Aug 2013
Zeng Zhiyu, Liu Yanqiong, Liu Zhiming, You Jianpeng, Chen Zhiping, Wang Jian, Peng Qiliu, Xie Li, Li Ruolin, Li Shan, Qin Xue
Abstract excerpt
PURPOSE: To evaluate whether breast cancer (BC) patients with CYP2D6 gene variation have different clinical tamoxifen (TAM) treatment outcomes to those with normal function of CYP2D6. METHODS: Systematic searches of the PubMed up to February 21, 2013, were retrieved. The study end points were disease-free survival (DFS) and overall survival (OS). Fixed or random-effects meta-analytical models were used to...
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