Article
Advanced maternal age impacts physiologic adaptations to pregnancy in vervet monkeys.
GeroScience - 1 Dec 2020
Plant Maren, Armstrong Cecilia, Ruggiero Alistaire, Sherrill Chrissy, Uberseder Beth, Jeffries Rachel, Nevarez Justin, Jorgensen Matthew J, Kavanagh Kylie, Quinn Matthew A
Abstract excerpt
The trend to delay pregnancy in the USA has resulted in the number of advanced maternal age (AMA) pregnancies to also increase. In humans, AMA is associated with a variety of pregnancy-related pathologies such as preeclampsia (PE). While AMA is known to be a factor which contributes to the development of pregnancy-induced diseases, the molecular and cellular mechanisms giving rise to this phenomenon are still...
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