SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: Insights into functional evolution and human genomics.

doi:10.1074/jbc.RA120.014873

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Article

SARS-CoV-2 (COVID-19) structural and evolutionary dynamicome: Insights into functional evolution and human genomics.

The Journal of biological chemistry - 14 Aug 2020

Gupta Ruchir, Charron Jacob, Stenger Cynthia L, Painter Jared, Steward Hunter, Cook Taylor W, Faber William, Frisch Austin, Lind Eric, Bauss Jacob, Li Xiaopeng, Sirpilla Olivia, Soehnlen Xavier, Underwood Adam, Hinds David, Morris Michele, Lamb Neil, Carcillo Joseph A, Bupp Caleb, Uhal Bruce D, Rajasekaran Surender, Prokop Jeremy W

Abstract excerpt

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has challenged the speed at which laboratories can discover the viral composition and study health outcomes. The small ∼30-kb ssRNA genome of coronaviruses makes them adept at cross-species spread while enabling a robust understanding of all of the proteins the viral genome encodes. We have employed protein modeling, molecular...

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Identifiers

PMID: 32587094
DOI: 10.1074/jbc.RA120.014873
PMCID: PMC7450099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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