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Article

Co-evolution of β-glucosidase activity and product tolerance for increasing cellulosic ethanol yield.

Biotechnology letters - 1 Nov 2020

Wang Kexin, Huang Qiuxia, Li Hanxin, Zhao Xihua

Abstract excerpt

β-Glucosidase (BGL) plays a key role in cellulose hydrolysis. However, it is still a great challenge to enhance product tolerance and enzyme activity of BGL simultaneously. Here, we utilized one round error-prone PCR to engineer the Penicillium oxalicum 16 BGL (16BGL) for improving the cellulosic ethanol yield. We identified a new variant (L-6C), a triple mutant (M280T/V484L/D589E), with enhanced catalytic...

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PMID: 32583369
DOI: 10.1007/s10529-020-02935-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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